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Research Interests

Our research interests include identifying fundamental mechanisms through which T cells are augmented as a result of inflammatory disease and/or identifying mechanisms through which mediators alter T cell function. 


Specifically, we are focused on two different disease states, hypertension and allergy/asthma.


Projects

  • Elucidating the impact of PGI2 on T regulatory Cell and dendritic cell function in hypertension.
  • Immune interplay in comorbidity models of hypertension and asthma
  • Viruses and cardiovascular disease
  • Tfh and Tfr cells in asthma
  • Ask for more details!

Active Funding

Norlander -  R00 HL159594 - 01/2023 - 12/2025

Norlander - Showalter Trust Young Investigator Award - 07/2024-06/2025

Norlander - IU Research Seed Grant - 01/2025-01/2026
 

Publications

PGI2 increases circulating Treg in human patients treated with a PGI2 analog for their PAH

AJRCCM

PGI2 promotes Treg function and stability in Models of Allergic airway inflammation

JCI

T cell SGK1 promotes hypertension

JCI Insight

IL-17A augments renal sodium transporter expression to promote salt and water retention in hypertension

Hypertension

Full List of Publications

NCBI

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